The abrupt cuts to USAID funding are hitting Africa’s healthcare systems hard, with HIV patients in South Africa already feeling the strain. Once-reliable drug deliveries have stalled, threatening lives and undoing decades of progress. The cuts slash billions in funding to programs battling HIV/AIDS, malaria, and tuberculosis across Africa, jeopardizing services for millions. From South Sudan’s cholera clinics to Somalia’s nutrition centers, the ripple effects are dire. Organizations like Amref Health Africa and Doctors Without Borders report widespread service collapse, and the Global Fund warns of resurgent epidemics. Yet, amid the crisis, countries like Uganda and Malawi are stepping up, vowing to fill the funding void. Still, experts warn that the cost of the cuts will soar if other donors follow the US’s lead.